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But these health issues may raise your risk: Diabetes High blood pressure High cholesterol Obstructive sleep apnea Taking certain medications (PDE4 inhibitors) Smoking Eye problems that can increase your risk include: Previous NAION in one eye A naturally crowded optic nerve (called disk at risk) Having prior eye surgery You can still take semaglutide or other GLP-1 drugs if you have these conditions
Researchers interested in GLP-1-based therapies may be familiar with liraglutide, classed along with semaglutide as a long-acting GLP-1RA hypoglycemic agent and approved for the treatment of type 2 diabetes and chronic weight management [17]
This may explain differences seen in outcomes for CV death between some diabetes CVOTs and renal and HF studies
Novo Nordisk has developed semaglutide, which is included in the best-selling drugs Ozempic and Wegovy, while Eli Lilly has developed tirzepatide, which is included in the market-leading drugs Mounjaro and Zepbound
The Bigger Picture: Tirzepatide as a Metabolic Game-Changer With its dual receptor action, weight loss benefits, and ability to enhance insulin sensitivity, Tirzepatide is revolutionizing diabetes and weight management
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