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4.2.1.2 Nephrotoxic mechanisms of indoxyl sulfate (IS) Indoxyl sulfate (IS) is one of the most representative protein-bound uremic toxins, formed from indole produced by gut microbiota metabolism of tryptophan through hepatic sulfation
Laptook AR, Salhab W, Bhaskar B
Archived from the original on 29 March 2023
The most effective option depends on individual health factors, goals, and response to treatment.
phosphonoglutamate analogs such as GGsTop and derivatives of the lead compound N-[5-(4-methoxybenzyl)-1,3,4-thiadiazol-2-yl]benzenesulfonamide, OU749, represent another class of GGT inhibitors (22)
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