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Peptide therapies require medical evaluation

10.1542/peds.2022-057092L 129 MantzarlisK.TsolakiV.ZakynthinosE

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Hyperplastic nodules of hepatocytes separated by septae of connective tissue can be seen in rats but is less common in mice

Injectable delivery remains the gold standard for systemic peptide therapies requiring maximum bioavailability and reproducible pharmacokinetics

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