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Staying well-hydrated helps regulate digestion, reduces headaches, supports energy levels, and may even reduce cravings

Management: Typically resolves within the first week

Weingart SD

Their combined application likely triggers overlapping and complementary pathways that boost antioxidant capacity ( mechanistic insights)

These benefits include attenuated inflammation and oxidative stress, enhanced endothelial function, vasodilation, and anti-atherosclerotic effects.6,33 Additionally, in one of the studies included in this systematic review of 55 patients with T2DM and PAD, the use of liraglutide improved peripheral perfusion, suggesting its potential to mitigate the clinical progression of PAD.17 In addition, the STRIDE trial (NCT04560998) is an ongoing study specifically designed to evaluate the impact of semaglutide on exercise capacity in patients with T2DM and intermittent claudication