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Tissue inhibitor of metalloproteinases protect blood-brain barrier disruption in focal cerebral ischemia

Unlike oral supplements, the injectable form delivers glutathione directly into tissue, which may help support more consistent absorption

These chemical components generally exert anti-AMS pharmacological effects by inhibiting the expression of VEGF (AMS marker), MDA, and pro-inflammatory factors (TNF-, IL-1, and IL-6), down-regulating NF-B/NLRP3 pathway, and promoting SOD and Na + -K + -ATPase activities, which attenuates acute hypobaric hypoxia-induced tissue injury

Wada, M

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