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It facilitated phosphorylation of eNOS at Ser1177, leading to increased NO production, primarily through estrogen receptor-mediated PI3K/Akt signaling

Call your doctor if the nausea is extreme or is not fading as time passes

Maintaining a symptom diary during your first two weeks allows you and your provider to identify patternssuch as nausea triggered by specific foodsthat inform your personal management plan and guide any needed adjustments to your treatment approach