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Having an oral option to deliver this highly effective therapy is a big advance. Results from the rather large, international trial were published in the New England Journal of Medicine and presented at the American College of Cardiologys Annual Scientific Session & Expo in Chicago, Illinois
The dual-agonist structure means a larger synthetic peptide, which may explain the higher rate of antibody formation and subsequent injection site reactions
The authors compared breast cancer incidence among 15,264 women with prior GLP-1 exposure 1 to the same number of women without exposure, with matching for age, BMI, breast density, race, ethnicity, and history of diabetes
Obesity is associated with chronically elevated sympathetic nervous system activity
Gupta said he's prescribed the weight loss drugs to 1,500 patients, with about 60% using compounded versions from a 503A pharmacy
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