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Mode of action Being a first-class compound that is orally active, Dihexa works through penetrating the blood-brain barriers
doi: 10.1128/AEM.02200-17, 31 CollinsonE
Circulation 121 , 22712283 (2010)
56 Small molecule targeted therapy (BRAF and MEK inhibitors) and immune checkpoint inhibitors (CTLA4 and PD1) have shown promising clinical outcomes
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