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Interact with neurotransmitter systems , possibly affecting serotonin, dopamine, and GABA signaling pathways
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In addition, the average BMI decreased from 43.1 to 41.5, and the average weight dropped from about 259 pounds to 246 pounds, with a third of patients losing 22 pounds or more during treatment
Taken together, our findings support the external validity of trial-based evidence and highlight the real-world effectiveness of tirzepatide in US clinical practice