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Similar to the early production of other viral vectors [26], a scale-out approach was employed with dozens of 10-layer cell stacks and several rounds of ultracentrifugation over multiple days

This gives you more information in regards to what would be the best treatment

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Next, the GSH linked with the active site cysteine residue of OsDHAR (enzyme-S-S-G) is removed by nucleophilic attack of the H-site bound GS

Atherosclerosis is aggravated by iron overload and ameliorated by dietary and pharmacological iron restriction