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Avoid non-breathable synthetics

While tirzepatide has not been shown to directly cause gastrointestinal ulceration in clinical trials, its effects on motility and bowel habits may create conditions where bleeding from benign sources becomes more likely

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[2] [5] At present, there are no GLP-1 patches licensed by the Medicines and Healthcare products Regulatory Agency (MHRA) or approved by the National Institute for Health and Care Excellence (NICE) for routine use in the United Kingdom (as verified through MHRA and Electronic Medicines Compendium searches, January 2024)