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Each choice is legitimate

Despite Harvard Medical School research published in July 2024 showing diabetes patients prescribed semaglutide faced over four times higher NAION risk (and weight loss patients faced over seven times higher risk) Novo Nordisks current Ozempic and Wegovy labels still mention only generic vision changes without specifically identifying NAION or permanent blindness as known risks

This occurs because the medication's appetite-suppressing signals fade once treatment ends

The pathways are entirely different

Y2R is widely expressed in multiple brain regions such as the amygdala, hippocampus, cortex, thalamus, lateral septum, olfactory nuclei and striatum (Caberlotto et al., 2006)