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Does Continuous Positive Airway Pressure Therapy in Patients with Obstructive Sleep Apnea Improves Uric Acid
Linked to pathways involved in energy balance at the cellular level
Gene expression studies reveal modulation of 408 neuronal genes, including dramatic increases in OPRM1 (opioid receptor, up 1,294%), KCND1 (up 845%), and SLC8A2 (up 737%)
In this context, research strategies aimed at the selective inhibition of FOXO proteins including the use of peptide analogs such as FOXO4-DRI represent a promising approach for investigating the modulation of metabolic pathways, with potential relevance to diabetes-related complications
Nanga RPR et al
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