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The DNA region spanning from 2 569 pb to + 310 pb of CCL11 (GRCh38/hg38 chr17: 3428317334286052) was amplified by PCR from bisulfite-converted DNA using a primer set designed to account for cytosine conversion to uracil (Bisulfite Primer Design Tool, Zymo Research) (Additional file 2) and GoTaq DNA Polymerase (Promega, Madison, Wisconsin)

Based on the establishment and development of the theory of the pathological roles of free radicals, the role of GPxs has gradually attracted researchers attention, and the involvement of GPxs in the occurrence and development of malignant tumors has been shown

Although certain NER gene mutations (ERCC6-Q524* and ERCC4-A583T) were found to be functionally associated with platinum sensitivity in vitro, these NER alterations did not affect HR or confer sensitivity to PARPis

Disease Prevention Cancer There has been considerable research on the effect of selenium supplementation on the incidence of cancer using preclinical models

Vitamin B12 also enables cell division and growth - critical processes for proper hair follicle function