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DHODH reduces CoQ's involvement in pyrimidine metabolism by promoting the oxidation of dihydroorotate (DHO) into orotate
Canaglifozin, dapaglifozin, and empaglifozin are the active substances approved in Europe and the USA as second-line treatment in association with metformin as well as third-line treatment [33]
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Fibre also slows digestion, helping to extend the release of GLP-1 over a longer period, supporting satiety and stable blood sugar levels
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