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1 2 3 The British Journal of Dermatology

As expected, in contrast to Dpp4 hep/ , Dpp4 EC/ mice had no decrease in hepatic Dpp4 mRNA expression (Supplemental Figure 2H), and, consistent with previous reports (38), systemic fasting plasma DPP4 activity and DPP4 protein levels (Supplemental Figure 2, I and J) were significantly decreased in Dpp4 EC/ mice compared with controls

These in vitro results have been replicated and published in peer-reviewed journals, and they form the strongest part of the evidence base