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Higher levels of ROS and inflammation within atherosclerotic lesions favor the loss of collagen and suppress its production

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[Abstract] The fluorescence intensity of MMP-2 in the HFSFs treated with glutathione oxidized (GLU, 2.48 mg/mL, 24 h) was 2.09 times greater than that in the HFSFs treated with ARP-100 (ARP, 100 M, 24 h)

Glutathione Reductase reduces oxidized glutathione (GSSG) to reduced glutathione (GSH) in the presence of NADPH