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However, new avenues are also being explored such as FOR-6219, a novel small molecule inhibitor of 17-Hydroxysteroid Dehydrogenase 1 developed by Organon, which blocks the formation of estradiol, reducing endometriotic lesions and pain without affecting natural hormone or ovarian function
MorganAPCrowleyJJNonnemanRJQuackenbushCRMillerCNRyanAKet al
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Body mass affects dosing and hangover, as a greater degree of adiposity can extend the drugs life and slow complete metabolic rebound after discontinuing therapy
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