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Sixty male, 5-wk old, wild-type C57BL/6J mice (JanVier Labs, France) were group housed in a controlled environment (12 h lightdark cycle, 21 2 C, 50 10% humidity) and fed the AMLN diet high in trans-fat, cholesterol, and fructose 46 ad libitum for 32 weeks to induce obesity and the NASH phenotype

GLP-1s are known to have positive cardiovascular effects, and better control of blood glucose levels through GLP-1 treatment has been shown to limit small blood vessel damage that can lead to health complications such as diabetic retinopathy

Easy Administration: Available in a 100ml sterile injection form, it can be administered intramuscularly or intravenously, with a recommended dosage of 3mL per 100kg of body weight

IM injection into a freshly trained muscle is reported in research interest in localized hyperplasia signaling, though the long half-life means the peptide distributes systemically regardless of site

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