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SNCA A53T and Gpx4 fl/fl were crossbred to obtain SNCA A53T / Gpx4 +/fl double transgenic hemizygous mice
Given how hard it is to get these medications for some patients, this can be an attractive alternative, but the FDA has expressed concern at the frequency of -glutide salts turning up in compounded formulations, which are not present in any of the FDA-approved drugs and thus have an unknown safety and efficacy profile
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Micha R, Pealvo JL, Cudhea F, Imamura F, Rehm CD, Mozaffarian D
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