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Expected changes: Significant appetite reduction, often described as forgetting to eat Accelerated weight loss compared to semaglutide baseline Potential for constipation as gastric emptying slows further Increased satiety lasting longer between meals Weeks 13 through 16: tirzepatide 10 mg At 10 mg, you are firmly in the therapeutic range that surpasses maximum semaglutide dosing
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At 5 foot 1, I was also clinically obese, with a worrisome family history
This prolonged gastric retention can increase intragastric pressure and potentially promote the reflux of stomach contents into the oesophagus, leading to symptoms of heartburn, regurgitation, and discomfort
In people with T2D and overweight/obesity, 16 weeks of danuglipron led to a placebo-adjusted WL up to 4.2 kg with the highest dose of 120 mg twice daily
