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Unlike other invisible conditions, vitiligo visibly alters physical appearance, sometimes in highly exposed areas (face, hands)
It helps protect the skin against early wrinkles and age-related dark spots
Contribution of the clock gene DEC2 to VEGF mRNA upregulation by modulation of HIF1 protein levels in hypoxic MIO-M1 cells, a human cell line of retinal glial (Mller) cells
This technology allowed us to perform comprehensive investigation of properties of target metabolites in the blood as well as to assess their levels in different population cohorts
Future research should focus on large-scale, well-controlled randomized trials with standardized dosing protocols, clearly defined deficiency thresholds, and long-term follow-up to strengthen the evidence base and guide clinical practice
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