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J Acquired Immune Deficiency Syndromes

This financial burden adds complexity to an already challenging situation for the estimated 38.4 million Americans living with diabetes

doi: 10.1210/jendso/bvab048.013

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Chronic hyperglycemia in diabetes downregulates GIP receptor (GIPR) expression and impairs GIP-mediated insulin secretion [21], rendering high-doses of GIP infusions ineffective [22]