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Pregnant or breastfeeding women are typically advised against use due to insufficient research

These persister cells act as a reservoir from which drug-resistant tumors can potentially emerge, making targeting them an attractive therapeutic opportunity to prevent tumor relapse

SDP has received research funding from AstraZeneca, Boehringer Ingelheim, Novartis Pharmaceuticals Co., and Merck Sharpe & Dohme, and is a consultant for or has received honoraria from AstraZeneca, Boehringer Ingelheim, Eli Lilly and Company, GlaxoSmithKline, Janssen Pharmaceuticals, Laboratoires Servier, Merck Sharp & Dohme, Novartis Pharmaceuticals Co., Novo Nordisk, Sanofi, and Takeda

It is thus imperative that interventions aimed at treating, and not just preventing, obesity are developed

The treatment group demonstrated measurable improvements in skin density, thickness, laxity, and fine lines compared to vehicle control