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The cleavable linker is designed to exploit specific environmental conditions at the target site, such as the acidic microenvironment of tumor tissues or the presence of certain enzymes within the tumor cells
Yin Z, Ivanov V, Habelhah H, Tew KD and Ronai Z
GSH AND OXIDATIVE STRESS The investigation on the field related to production of ROS/RNS during metabolic processes, even under physiological conditions, unlocks another branch of research focusing on the role of GSH ranging from antioxidant/radical scavenger to redox signaling modulator
Front Biosci (Schol Ed) 3:12161231 Gu Y, Zheng G, Xu M, Li Y, Chen X, Zhu W, Tong Y, Chung SK et al (2012) Caveolin-1 regulates nitric oxide-mediated matrix metalloproteinases activity and bloodbrain barrier permeability in focal cerebral ischemia and reperfusion injury
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