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The second group was intraperitoneally injected with DEX (10 mg/kg) on alternate days for 28 days to induce hepatic and oxidative damage

This may be done by recycling glutathione into its active form (recall the reduced form of glutathione, GSH!) that can neutralize free radical activity

doi: 10.1136/bmj.n71 13 HigginsJPAltmanDGGtzschePCJniPMoherDOxmanADet al

Then on the molecular level, our team recently showed, in collaboration with Dr Marisa Roberto from Scripps in La Jolla, California, that semaglutide may in fact change the GABA transmission at the level of some brain regions, such as the amygdala and the prefrontal cortex

This dual effect helps lower blood glucose levels and improves insulin sensitivity