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Thus, residues Tyr110 and Lys105 might share a function in accordance with the glutathione activator model but might also differ, for example, regarding the protonation state of the active site cysteine residue
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Because GSH rapidly oxidizes outside cells, variables like collection time, processing delays, temperature, and anticoagulants significantly affect accurate measurement, particularly in the unstable reduced fraction of GSH [118]
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