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To understand why these receptors matter, it helps to start with the physiology the whole class exploits: the incretin effect
Accessed at www.who.int/news/item/19-06-2024-medical-product-alert-n-2-2024falsifiedozempic-(semaglutide)
Large meals combined with slowed gastric emptying (a direct effect of GLP-1 receptor activation) create discomfort, bloating, and nausea
Out of 1,000 candidates, they found only four possible options
Others include glucose-dependent insulinotropic polypeptide (GIP), ghrelin, peptide YY (PYY) and pancreatic polypeptide (PP) (1)
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