Clinical scenarios warranting consideration of GLP-1 therapy include: Type 2 diabetes management : Per ADA 2024 Standards of Care, GLP-1 RAs may be considered as initial therapy in patients with established atherosclerotic cardiovascular disease (ASCVD), high ASCVD risk, chronic kidney disease (CKD), or heart failure, or as add-on therapy when glycemic targets aren't met Established cardiovascular disease : Several GLP-1 receptor agonists have demonstrated cardiovascular risk reduction in patients with type 2 diabetes and established ASCVD Chronic kidney disease : While SGLT2 inhibitors are generally prioritized for CKD with type 2 diabetes when eGFR allows, GLP-1 RAs may provide complementary benefits Obesity with complications : When lifestyle interventions produce insufficient weight loss in patients with obesity-related comorbidities Important safety considerations include: Contraindications : Personal or family history of medullary thyroid carcinoma or multiple endocrine neoplasia syndrome type 2
Meringankan efek samping kemoterapi pada pasien kanker Pemberian suplemen glutathione kepada pasien kanker yang menjalani kemoterapi terlihat dapat meringankan efek samping kemoterapi, seperti sariawan dan radang kerongkongan
Qu dice la evidencia: La L-arginina tiene una funcin fisiolgica real, pero sus efectos como suplemento dependen de la dosis, la persona, el objetivo, la forma usada y el contexto
It is a popular term for higher intestinal permeability, meaning the barrier is more open than it should be
Frontiers in Neuroscience , 7:181
