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Aziz TA, Hussain SA, Mahwi TO, Ahmed ZA, Rahman HS, Rasedee A

When a microcapsule preparation of cetrorelix was compared with microcapsules of agonist [d-Trp6]-LH-RH in rats bearing Dunning R-3327H prostate carcinoma, cetrorelix caused greater inhibition of prostate cancer growth than [d-Trp6]-LH-RH 27 , and decreased testosterone levels to non-detectable values, and LH levels were also diminished

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Two of the three groups were transitioned from WD to LD for 5 days before the start of the study