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10.1016/j.fct.2015.03.020 73 OoiJ
Hepatic PGC-1 overexpression markedly increases lipogenic genes even under APAP challenge In the liver, PGC-1 plays a major role in the synthesis of new fatty acids and VLDL excretion
These processes contribute to ROS and RNS overproduction and oxidative stress which intensifies cytokine secretion in keratinocytes (163)
3.1 BCS Class I: High Solubility, High Permeability 3.1.1 Warfarin Warfarin is an anticoagulant with a narrow therapeutic index, assessed by measurement of the INR
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