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"Supplements can't replace the medication" doesn't mean "supplements do nothing." Your body does produce its own GLP-1 in response to food, and certain dietary choices and ingredients can support healthy blood sugar, digestion, and satiety

A lot of compounded drugs come in units, Simonetti says

Weight loss is another potential benefit, as obesity can heighten inflammation in the body, possibly worsening lupus symptoms

Your provider may recommend slowing dose titration, temporarily reducing the dose, or implementing additional management strategies if symptoms are severe or persistent