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Wegovy remains a popular choice as a leading injectable semaglutide, administered weekly via a pre-filled pen device
Resmetirom a thyroid hormone receptor- agonist is currently the only drug with (accelerated) approval from the US Food and Drug Administration for treating MASH with fibrosis
It has been rigorously tested for this use and is considered safe for most adults when managed by a physician
Researchers designing long-term protocols might consider whether the additional 3 percentage points of weight loss at 12mg versus 8mg justifies the higher dropout risk for their specific application
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