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Top-Selling Medicines in 2025 H1: GLP-1 in the New Drug Vanguard The first half of 2025 saw GLP-1-based therapies cement their status among the worlds highest-grossing drugs

Frias JP, Davies MJ, Rosenstock J et al (2021) Efficacy and safety of tirzepatide vs

All GLP-1 RAs other than Saxenda and Wegovy have the indication of T2DM and are subsidized only for patients with T2DM who first tried metformin, sulphonylureas or insulin, or where these are not appropriate