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Sleeve = GIP + GLP-1 Your intestines are still in their normal layout so food passes through both hormone zones, giving you a two-for-one effect
![semaglutide lean mass loss Tirzepatide vs. Semaglutide: Which GLP-1 Better Preserves Muscle? [SURMOUNT-5 Data] Semaglutide Muscle Loss - A](https://www.tandfonline.com/cms/asset/08c0cb66-c1b9-4047-932c-f097db44f2a3/dddt_a_12314606_f0002_c.jpg)
Statistical analysis The sample size possessing sufficient statistical power for each experiment is provided in the figures or mentioned under respective sub-headings in the methods section
![semaglutide lean mass loss Tirzepatide vs. Semaglutide: Which GLP-1 Better Preserves Muscle? [SURMOUNT-5 Data] Semaglutide Muscle Loss - A](https://pro.novonordisk.ae/content/dam/hcp-plus/ae/en/scientific-hub/novo-nordisk-medical-education/step-up-semaglutide-improves-body-composition-with-preserved-muscle-function/images/step-up-semaglutide-improves-body-composition-with-preserved-muscle-function-weight-loss-distribution.png)
Marc Jean-Gilles, DO, FACOG
![semaglutide lean mass loss Tirzepatide vs. Semaglutide: Which GLP-1 Better Preserves Muscle? [SURMOUNT-5 Data] Semaglutide Muscle Loss - A](https://lookaside.instagram.com/seo/google_widget/crawler/?media_id=3937511336493682496)
The pharmacological action of GLP-1 is to promote -cell regeneration, growth and differentiation, and to inhibit -cell apoptosis
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