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2,47,48 A Cochrane review of six double-blind trials (n = 438) of tramadol demonstrated a number needed to treat of 5 (95% CI, 2.9 to 8.8) for one additional participant to experience a 50% pain reduction
There is no evidence so far that this heart rate increase leads to heart damage or dangerous arrhythmias in healthy individuals, but monitoring may be recommended in patients with existing cardiovascular disease
May your formulations stay potent, your muscle mass stay protected, and your protocols stay consistent.
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