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As a diagnostic agent, a single intravenous dose of sermorelin (about 1 g/kg) was used as a provocative test of pituitary GH-secretory capacity, notable for producing relatively few false-positive results compared with some other provocative tests

Occasional digestive irregularities persist for some

These medications work through multiple complementary mechanisms that collectively promote weight loss and metabolic improvement

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Here is what the 24-week results showed across the main dose groups: 4 mg group lost an average of 7.9% body weight 8 mg group lost an average of 12.9% body weight 12 mg group lost an average of 17.5% body weight Placebo group lost an average of 1.6% body weight Higher doses work faster and produce larger total weight loss