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The sensitivity of CEST MRI is increased by up to two orders of magnitude compared to MRS via continuous magnetic saturation of metabolite protons and subsequent exchange with bulk water protons over a period of seconds
A change in a methyl-donor pool is not automatically beneficial and may vary between tissues
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a lapsed license results in immediate removal from the directory
To enhance the immunogenicity of peptide-based cancer vaccines, conjugates and polymers can be used to target peptides to specific immune cells or to include stimulation molecules
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