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It activates the GIP receptor with approximately equal potency to native GIP, but activates the GLP-1 receptor with roughly five times lower potency than native GLP-1
Tirzepatide, which is sold under the brand name Mounjaro for diabetes and Zepbound for weight loss, is similar to semaglutide, but is a GLP-1/GIP agonist
J., & Kalman, D
The FDA-approved maximum weekly dose for weight management (Wegovy) is 2.4 mg
Pharmacokinetics and effects on cyst(e)ine in plasma and urine Saitoh T., et al
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