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In the treatment of breast cancer, anti-estrogen tamoxifen, the drug most often used for the long-term treatment of early breast cancer, can induce apoptosis in many cells, and this effect may be mediated by ROS generation in the mitochondria of breast cancer cells [71]

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Biomed Pharmacother (2008) 62(4):23649.10.1016/j.biopha.2008.01.017 9 HwangO

Some studies conclude on the causal link between the Fmr1 -KO and abnormal expression of the synaptic mitochondrial proteins

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