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The net result is a shift toward fat oxidation rather than fat storage

These findings suggest that DMF, in addition to NRF2 activation on antioxidant response, could affect L2HGDH expression, L2HG and SAM levels to modify DNA 5mC and 5hmC modifications and CBS expression in SCD erythroblasts

Liver fibrosis represents, together with the comorbidities of metabolic syndrome, a significant prognostic determinant in NAFLD