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Acknowledgements This work was supported by grant BK20140049 from the Jiangsu Province Funds for Distinguished Young Scientists, BK20161082 from the Natural Science Foundation of Jiangsu Province and from the National Natural Science Foundation of China(NOs 81274150, 81403092, 81573964)

J Biol Chem 259(15):95089513 Finkelstein JD, Martin JJ, Kyle WE, Harris BJ (1978) Methionine metabolism in mammals: regulation of methylenetetrahydrofolate reductase content of rat tissues

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