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L-Arginine remains the largest sourece of nitrogen int he body for NO production, its relevance and metabolism of NO has received much attention over the last decade

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Interestingly, introduction of carboxylic acid groups to RT slows down its reaction kinetics towards GSH comparing to RT-NH 2 and TQG-CN (Table 2), presumably due to the charge repulsion between the carboxylic acid groups and the anionic GSH