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A histopathologic examination can confirm the MNTI diagnosis by identifying two distinct cell populations: small round cells and larger melanocyte-like cells containing dark brown pigment, set in a fibrillary and collagenized vascular stromal background (Asefa and Hailu 2024)
Consistent with these observations, patients included in the studies analyzed in this systematic review frequently reported significant cardiometabolic benefits in addition to BW loss
Trougakos et al., 2021)
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