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Compared with participants who received placebo injections, those treated with semaglutide showed: Slower biological aging across multiple epigenetic clocks tied to inflammation and the health of the blood, brain, heart, kidneys, liver, and metabolism

For example, studies involving GLP-1 RAs have been shown to reduce major adverse cardiovascular events in patients with T2DM

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In a meta-analysis of cohort studies that reported on outcomes of GLP-1 RAs in adult kidney transplant recipients, no significant changes in eGFR (95% CI 0.64-0.50

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