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Under the proposed plans outlined by NICE, to be eligible to receive the drug first, patients would need to have BMI over 40 and at least three specified weight-related health problems: hypertension, dyslipidaemia, obstructive sleep apnoea, or cardiovascular disease
NMJ dysfunction and instability is a frequently encountered electrophysiologic finding in the evaluation of ALS [282]
Genes with a twofold change were considered differentially expressed
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